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PNS

  • Microelectrode Arrays for Pain Research and Drug Development

    September 27, 2013

    Microelectrode Arrays for Pain Research and Drug Development

    Large amounts of information on the cellular and molecular mechanisms involved in sensory processing in the peripheral nervous system have been gained in vitro using neurons isolated from dorsal root ganglia (DRG). Electrophysiological recordings from cultured DRG neurons were mainly obtained by the use of patch-clamp, an approach offering a level of throughput often incompatible with the objectives of the pharmaceutical industry.

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